Hemostasis Today

Factor X Deficiency – From Mild Bruising to Life Threatening Hemorrhage – ICHCC
May 30, 2026, 10:17

Factor X Deficiency – From Mild Bruising to Life Threatening Hemorrhage – ICHCC

Iranian Comprehensive Hemophilia Care Center (ICHCC) shared a post on LinkedIn:

Factor X deficiency, or Stuart-Prower factor deficiency:

  • is an ultra-rare bleeding disorder caused by a lack or dysfunction of Factor X—a critical protein required for blood clotting. Affecting about 1 in 500,000 to a million people, it can be inherited genetically or acquired later in life.
  • Symptoms and ComplicationsSeverity is generally classified by the amount of circulating Factor X in the blood:Mild (40% – 60% of normal): Easy bruising, mild nose or mouth bleeds, and bleeding after trauma or surgery.Moderate (10% – 40% of normal): Spontaneous minor bleeds, heavy periods, or prolonged bleeding after dental procedures.Severe (<10% of normal): High risk of spontaneous, life-threatening hemorrhages (such as intracranial bleeds), joint/muscle bleeds, and umbilical cord bleeding in newborns.”

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