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Ifeanyichukwu Ifechidere: The Role of Coagulation in Anaesthesia and Surgery

Ifeanyichukwu Ifechidere/LinkedIn

Nov 10, 2026, 14:49

Ifeanyichukwu Ifechidere: The Role of Coagulation in Anaesthesia and Surgery

Ifeanyichukwu Ifechidere, Specialist Biomedical Scientist at Sheffield Teaching Hospitals, shared a post on LinkedIn:

“What does coagulation have to do with anaesthesia? more than you might think!

Imagine preparing a patient for surgery.

The anaesthetic plan is ready, the theatre is booked, and everything seems to be in place.

But one important question remains:

Is this patient’s blood able to clot appropriately, and is it safe to proceed?

This is where understanding haemostasis and coagulation becomes essential in anaesthesiology.

Coagulation isn’t just a topic for haematologists and biomedical scientists. It plays a significant role in perioperative patient safety.

Let’s look at four important areas where coagulation knowledge makes a difference.

1. Assessing coagulation before surgery

Before an operation, clinicians need to consider the patient’s bleeding history, medical conditions, medications and relevant laboratory results. investigations may include:

PT INR
APTT
Platelet count
Fibrinogen
Specific coagulation factor assays

Understanding what these results mean helps identify potential bleeding risks and guides further investigation.

2. Guiding transfusion decisions

Unexpected bleeding during surgery can become a critical situation.

Understanding coagulation helps anaesthetists recognise whether the problem involves:

Clotting factor deficiency
Low fibrinogen
Thrombocytopenia or platelet dysfunction
Excessive fibrinolysis

This knowledge supports targeted transfusion decisions rather than simply giving blood products without understanding the underlying problem.

3. Regional anaesthesia safety

Have you ever wondered why coagulation status matters before an epidural or spinal anaesthetic?

Bleeding into a confined space around the spinal cord can cause a spinal or epidural haematoma, a potentially devastating complication.

Understanding platelet function, coagulation abnormalities and anticoagulant use is therefore essential when assessing the safety and timing of neuraxial procedures.

4. Perioperative anticoagulant management

Many patients coming for surgery are already taking anticoagulants.

Think about:

Warfarin
Apixaban
Rivaroxaban
Dabigatran
Heparin

The anaesthetic team needs to understand the indication, last dose, renal function, bleeding risk and procedure-related risks when planning interruption and resumption.

The timing depends on the individual drug, dose, renal function and procedure. Some situations require specific laboratory investigations or specialist advice.

The Big Takeaway

Coagulation knowledge is not confined to the coagulation laboratory.

It connects the laboratory, anaesthetist, surgeon and clinical team in making safer decisions for patients.

Behind every PT, APTT, fibrinogen or anti-Xa result is information that can influence clinical management.

Save and share this post with someone working in perioperative care.

And follow me for more practical, simplified educational content on coagulation.” Ifeanyichukwu Ifechidere: The Role of Coagulation in Anaesthesia and Surgery