Mahesan Subramaniam: Raspberry Support Heart, Brain, and Metabolic Health
Mahesan Subramaniam, Co-Founder of United Health Tourism, posted on LinkedIn about a recent article by Britt M Burton-Freeman, published in Advances in Nutrition։
”The antioxidants in raspberries, particularly anthocyanins, act as biological ‘switches’ that dampen the body’s inflammatory response. Anthocyanins block the activation of NF-kB, a master regulator that triggers the production of pro-inflammatory cytokines.
Compounds like ellagic acid and Quercetin block enzymes that cause pain and swelling, such as those associated with arthritis.
The combination of fiber and polyphenols (like ellagitannins) strengthens the intestinal barrier, preventing toxins from entering the bloodstream and causing systemic inflammation.
Raspberry antioxidants protect the cardiovascular system by improving how blood vessels function and reducing structural strain. Anthocyanins increase nitric oxide production, which helps blood vessels relax (vasodilation), improving circulation and lowering blood pressure. High fiber and polyphenols work together to reduce LDL (bad) cholesterol and prevent it from oxidizing, which keeps plaque from building up in the arteries (atherosclerosis).
Lab studies show that raspberry extracts can reduce oxidative stress in heart cells and prevent harmful remodeling (scarring) of heart tissue during failure.
The long-term protective effects of these antioxidants also target the root causes of major health conditions.
Ellagitannins can induce apoptosis (programmed cell death) in cancer cells and inhibit angiogenesis, the formation of new blood vessels that feed tumors. They also help repair DNA damage that could otherwise lead to mutations. Furthermore, anthocyanins improve insulin sensitivity, helping the body to process glucose more efficiently and reducing the inflammation that contributes to type 2 diabetes.
Antioxidants like Quercetin and vitamin C cross the blood-brain barrier to reduce neuroinflammation and oxidative stress, which are linked to cognitive decline and disorders like Alzheimer’s and Parkinson’s.”
Title: Red Raspberries and Their Bioactive Polyphenols: Cardiometabolic and Neuronal Health Links
Authors: Britt M Burton-Freeman, Amandeep K Sandhu, Indika Edirisinghe

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