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Rupam Manna: Thrombocytopenia in Oncology – Complete High-Yield Guide for Safe Chemotherapy Delivery
Rupam Manna/LinkedIn
May 9, 2026, 22:18

Rupam Manna: Thrombocytopenia in Oncology – Complete High-Yield Guide for Safe Chemotherapy Delivery

Rupam Manna, Postdoctoral Student – DrNB Medical Oncology at National Board of Examinations, shared a post on LinkedIn:

”Thrombocytopenia in Oncology – Complete High-Yield Guide for Safe Chemotherapy Delivery!

From definition and grading to all causes (CIT, marrow infiltration, radiation, immune-mediated, hypersplenism, DIC) – clinical manifestations – evaluation – platelet thresholds for chemo and procedures – impact on treatment outcomes.

Key sections:

  • Common culprit drugs (carboplatin, gemcitabine, temozolomide, PARP inhibitors, checkpoint inhibitors & more)
  • Practical platelet thresholds for chemo, central lines, LP, surgery
  • Treatment ladder: Transfusions, chemo modification, TPO-RAs (romiplostim, eltrombopag, avatrombopag)
  • Prophylaxis and important oncology pearls (carboplatin nadir, persistent thrombocytopenia clues)

Reduces delays, dose reductions and improves quality of life plus survival!”

Rupam Manna: Thrombocytopenia in Oncology - Complete High-Yield Guide for Safe Chemotherapy Delivery

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