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Tareq Abadl: Has Anyone Here Ever Taken an ALP Test Before?
Mar 15, 2026, 13:45

Tareq Abadl: Has Anyone Here Ever Taken an ALP Test Before?

Tareq Abadl, Medical Laboratory Specialist and Director of the Blood Bank at Dr. Abdelkader Al-Mutawakkil Hospital, shared a post on LinkedIn:

“Has anyone here ever done an ALP (Alkaline Phosphatase) test before?

This enzyme is measured in the blood and is mainly found in:

  • Liver
  • Bones
  • Intestines
  • Placenta during pregnancy

The normal range isn’t a single fixed number, it varies depending on:

Age: Children usually have higher levels because of bone growth.
Gender: Slight differences between men and women.
Pregnancy: Levels can be higher due to the placenta.

Labs also set ranges depending on the devices and methods used.

Practical steps of the test in the lab:

  1. Sample collection: Venous blood (Serum or Plasma).
  2. Preparation: The sample must be free of hemolysis to avoid false results.
  3. Storage: If not analyzed immediately, keep at 2–8°C.
  4. Measurement: Automated chemistry analyzers measure enzyme activity at alkaline pH.
  5. Result: A number compared to the reference range for age and gender.
  6. Interpretation: The number alone isn’t enough; it must be compared with other tests like LFTs or Bone profile.

High ALP may indicate:

  • Blocked bile ducts or liver diseases like hepatitis, cirrhosis, liver tumors.
  • Bone diseases like osteomalacia, fractures, bone tumors, or Paget’s disease.
  • Normal in children during growth or after bone healing.
  • Can rise with certain medications (e.g., anti-epileptics, contraceptives).
  • May increase in pregnancy due to the placenta.

Low ALP may be linked to:

  • Malnutrition or deficiency of zinc and magnesium.
  • Genetic hypophosphatasia.
  • Severe anemia or thyroid problems.
  • Sometimes after blood transfusion or in rare conditions.

Examples for practical interpretation:

  • Patient with high ALP plus jaundice/itching – think liver.
  • Patient with bone pain or repeated fractures – think bones.
  • Child – often normal due to growth.
  • Pregnant woman – may be normal due to placenta.
  • If unclear – order extra tests like GGT, Calcium, Vitamin D.”

Tareq Abadl

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