Christina Pohlman: Could aPL Levels Help Predict Stroke Recurrence?
Christina Pohlman, CEO and Co-Founder of APS Foundation of America, shared a post on LinkedIn about a recent article by Macy L E Gatti et al., published in RPTH, adding:
“Could the level of persistent antiphospholipid antibodies help tell us more about stroke recurrence?
A new study followed 47 people who had experienced a cryptogenic stroke or TIA and continued to test positive for antiphospholipid antibodies (aPLs) for at least 12 weeks.
Researchers found that recurrent ischaemic stroke was less common in people with weakly positive aPLs than in those with strongly positive aPLs.
Treatment patterns also differed: antiplatelet medicines were recommended more often in the weakly positive group, while warfarin was more commonly recommended for those with strongly positive aPLs.
It’s an interesting finding, but the study was small, retrospective and carried out within one health system.
The researchers say larger prospective studies and randomized trials are needed to better understand the best treatment approach.”
Title: Management and outcomes in patients with cryptogenic stroke and weakly positive antiphospholipid antibodies
Authors: Macy L E Gatti, Steven R Messé, Adam Cuker
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