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Specific Reversal Agents for Direct Oral Anticoagulants in Neurosurgical Emergencies
Laura Zeller/LinkedIn and Menno Germans/LinkedIn
Dec 20, 2025, 07:41

Specific Reversal Agents for Direct Oral Anticoagulants in Neurosurgical Emergencies

RPTH Journal shared a post on LinkedIn:

“In emergency neurosurgery, rapid DOAC reversal is critical. This systematic review evaluates perioperative outcomes of idarucizumab and andexanet alfa, highlighting evidence gaps and safety insights.

If you work in hemostasis, neurosurgery, or acute care, this one’s worth a look.

Senior Author: Menno Germans”

Title: Specific reversal agents for direct oral anticoagulants in neurosurgical emergencies – a systematic review

Authors: Laura Zeller, Jonas Rohr, Giovanna Brandi, Christoph Globas, Alexander Kaserer, Matthias Greutmann, Tilman Schubert, Jan-Dirk Studt, Katharina Geiling, Luca Regli, Menno R. Germans

Specific Reversal Agents for Direct Oral Anticoagulants in Neurosurgical Emergencies

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acute care Alexander Kaserer Andexanet Alfa Christoph Globas DOAC Giovanna Brandi Health Hemostasis Hemostasis Today idarucizumab Jan-Dirk Studt Jonas Rohr Katharina Geiling Laura Zeller Luca Regli Matthias Greutmann Medicine Menno R. Germans Neurosurgery thrombosis Tilman Schubert
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