Decoding the Inflammatory–Metabolic Axis in Atherosclerosis: A New Frontier in Cardiovascular Prevention- by Atherosclerosis
Atherosclerosis published on X:
“Metabolic, renal, and inflammatory crosstalk in atherosclerotic cardiovascular disease: Evolving landscape and future directions.”
Title: Metabolic, renal, and inflammatory crosstalk in atherosclerotic cardiovascular disease: Evolving landscape and future directions.
Authors: Harris Avgousti, Matthew J. Feinstein
This recent publication in Atherosclerosis explores the complex interplay between metabolic dysfunction, renal impairment, and systemic inflammation in driving atherosclerotic cardiovascular disease (ASCVD). The review highlights how shared molecular pathways—such as oxidative stress, cytokine cascades, and metabolic-renal feedback loops—converge to accelerate plaque progression and vascular injury.
The authors emphasize a paradigm shift toward integrated, multi-system prevention strategies, including anti-inflammatory therapies, metabolic modulation, and kidney function preservation. This evolving understanding holds promise for personalized ASCVD management and novel therapeutic targets.
Read the abstract: Atherosclerosis Journal (June 2025).
See more in Hemostasis Today.
-
Dec 12, 2025, 23:51Don’t Miss: IACH Post ASH 2025 Roundtable Debate
-
Dec 12, 2025, 23:37C-Reactive Protein and Cardiovascular Risk in the General Population: A European Heart Journal Study by Berkan Kurt et al.
-
Dec 12, 2025, 23:23Alta Schutte and Colleagues at National Hypertension Taskforce: Driving Single-Pill Therapy for Hypertension and More
-
Dec 12, 2025, 22:27Normal Counts, High Risk: Abdul Mannan Breaks Down JAK2 + Splanchnic Vein Thrombosis
-
Dec 12, 2025, 14:478 Posts Not to Miss From the ASH 2025 – Marc Carrier
-
Dec 12, 2025, 10:17Alyssa George on Clinical and Economic Impact of a Eptacog Beta
-
Dec 12, 2025, 09:53Ivan Budnik Awarded AHA Postdoctoral Fellowship! Aiming to Improve DVT Long-term Outcomes
-
Dec 12, 2025, 09:34Giles Platford on Baby Big: Plasma-Derived Drug Against Infant Botulism
-
Dec 12, 2025, 09:22Matteo Foschi Presents The New Expert Guidance on Minor Ischemic Stroke