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D Dimer Role in Coagulation Activation and Secondary Fibrinolysis
Sep 25, 2025, 10:31

D Dimer Role in Coagulation Activation and Secondary Fibrinolysis

Bruno Pougault, Global Marketing Hemostasis Product Manager at HORIBA, reposted from Horiba on LinkedIn:

”D dimer is an important biomarker of coagulation activation and secondary fibrinolysis that is routinely used to rule out venous thromboembolism (VTE), and to evaluate the risk of VTE recurrence, as well as the optimal duration of anticoagulant therapy.”

Horiba for Healthcare shared on LinkedIn:

”[Register now!] Free Online Workshop

D-Dimer: Diagnostic Challenges and Clinical Relevance

Thursday, October 16, 11–12 AM CEST

Register here.

This online workshop will focus on D dimer, a byproduct of the blood clotting and breakdown process that serves as a marker of ongoing coagulation and fibrinolysis.

The session will explore its clinical use in ruling out deep vein thrombosis (DVT) and pulmonary embolism (PE), as well as the inherent challenges—such as poor specificity, false positives, and difficulties in interpretation, especially in older patients or those with conditions like COVID-19 or cancer.

Participants will learn how to improve diagnostic accuracy and patient management through the use of clinical pretest probability assessments.

The workshop will also discuss the application of age-adjusted D dimer thresholds and the importance of confirmatory imaging in guiding clinical decisions.

Who should attend?

Healthcare professionals involved in D-dimer testing and thromboembolic disease management, such as pathologists, hemostasis lab scientists, acute care nurses, emergency physicians, hospitalists, hematologists, cardiologists, geriatricians, general practitioners, and trainees in related specialties.”

D Dimer Role in Coagulation Activation and Secondary Fibrinolysis

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