Jun 24, 2025, 11:32
Don’t Check for FV Leiden OR Do? | Latest JAMA Insights
JAMA lately posted on X:
“JAMA Insights: Testing for factor V Leiden in patients with venous thromboembolism should only be performed when the results may affect management decisions about anticoagulation.”
Check out the full article here.
Perhaps your patient suffers from venous thromboembolism. First question to ask yourself: Will checking ‘’Leiden’’ affect my clinical judgement?
According to Karlyn A. Martin et al., testing for F V Leiden should be preserved for cases when the results are actually going to affect the anticoagulation management of your patient.
- Pregnancy with family history of VTE ? You definetely should!
- What if Unprovoked VTE? Think twice before checking!

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