Adishwar Rao: LAAC vs Oral Anticoagulation in Atrial Fibrillation
Adishwar Rao, IM Resident at Guthrie Clinic, shared a post on X about a recent article he and his colleagues co-authored, published in CirculationEP, adding:
”Thrilled and grateful to share our recent publication in CirculationEP, comparing left atrial appendage closure (LAAC) with oral anticoagulation in atrial fibrillation.
Across 6 RCTs and over 7k patients: LAAC was associated with a higher risk of ischemic stroke but a lower risk of nonprocedural major bleeding.
Overall stroke, major bleeding, and mortality were not significantly different.”
Title: Left Atrial Appendage Closure Versus Oral Anticoagulation in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Adishwar Rao, Venkatesh Ravi, Mukunthan Murthi, Rahul Chikatimalla, Vennela Talla, Nihal Nagaraj, Gaurav Dhar, Neeraj Jolly, Aviral Vij

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