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Benjamin Vipler on D-dimer Cutoff Safely Ruling Out DVT
Jan 18, 2026, 13:41

Benjamin Vipler on D-dimer Cutoff Safely Ruling Out DVT

Benjamin Vipler, Associate Professor of Medicine at University of Colorado School of Medicine, shared on LinkedIn:

”An age-adjusted D-dimer cutoff may safely rule out DVT and increase diagnostic efficiency, reducing the need for unnecessary imaging.”

This multicenter prospective study evaluated whether an age-adjusted D-dimer cutoff can safely exclude deep vein thrombosis (DVT) in outpatients with suspected disease.

Among patients with low or unlikely clinical probability, using the age-adjusted cutoff increased the number of negative D-dimer results—especially in older patients—without missed venous thromboembolic events during 3-month follow-up.

These findings support the safety and clinical value of age-adjusted D-dimer thresholds to improve diagnostic efficiency in suspected DVT.

Read the full article here.

Article: Age-Adjusted D-Dimer Cutoff Levels to Rule Out Deep Vein Thrombosis

Authors: Grégoire Le Gal, Helia Robert-Ebadi, Venkatesh Thiruganasambandamoorthy et al.

Benjamin Vipler on D-dimer Cutoff Safely Ruling Out DVT

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