Jean-Jacques Kiladjian: Interferon-Alpha in Polycythemia Vera Balancing Efficacy and Autoimmune Risk
Jean-Jacques Kiladjian, Head of Clinical Research Department of Inserm, Professor of Medicine at the University of Paris Cité, President of the FIM, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in HemaSphere, adding:
“Interferon-alpha is a major treatment for Polycythemia Vera, but its use requires some precautions, particularly due to its immunomodulatory properties. In this article, we review the immune-related complications associated with interferon-alpha therapy and discuss strategies for their prevention and management.
A pre-treatment evaluation is necessary, and discussion with a specialist is often helpful to determine whether interferon can be safely used and how patients should be monitored in the presence of pre-existing autoimmune disease or signs of autoimmunity.”
Title: Autoimmunity and peginterferon therapy for polycythemia vera
Authors: Etienne Rivière, Alexandre Guy, Olivier Mansier, Clémence Mediavilla, Jean-Jacques Kiladjian, Chloé James, Patrick Blanco, Estibaliz Lazaro, Jean-François Viallard
More posts featuring Jean Jacques Kiladjian on Hemostasis Today.
-
Aug 10, 2026, 11:19Rishdha Roshad: Hemodilution vs Transfusion on CPB – Balancing Oxygen Delivery and Microcirculatory Flow
-
Aug 10, 2026, 11:15Julie McMullen: CSANZ Heart Failure Stream – Latest Updates on Atrial Myopathy and AFib
-
Aug 10, 2026, 11:07Praveen Kaudlay: A Deep Dive into Hemophilia Care Progress with Dr. Suresh Hanagavadi
-
Aug 10, 2026, 10:59Christian Heiss: Paclitaxel Efficacy in Dialysis-Dependent PAD
-
Aug 10, 2026, 10:52Seth Masters: Blocking the Effect of Pyrin by Targeting IL-1
-
Aug 10, 2026, 10:47Sadia Kamal: Making Connections and Sharing Science at Hemostasis GRC
-
Aug 10, 2026, 10:34Ifeanyichukwu Ifechidere: TTP and ADAMTS-13 – The Enzyme Deficiency That Can Kill in 24 Hours
-
Aug 10, 2026, 10:30Mansi Kala: Key Takeaways from NHU 2026 in Haemostasis and Laboratory Practice
-
Aug 10, 2026, 08:41Gut Microbiota and Platelet Recovery After Radiation – Platelets Journal