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Classification of Anaemia: Three Main Ways by Samwel Mikaye
Dr. S.0 MIKAYE / LinkedIn
Jan 6, 2026, 08:16

Classification of Anaemia: Three Main Ways by Samwel Mikaye

Samwel Mikaye, CEO of SaMik Medical Center, shared on LinkedIn:

“CLASSIFICATION OF ANAEMIA

Anaemia can be classified in three main ways:

1. MORPHOLOGICAL CLASSIFICATION

(Based on RBC size and hemoglobin content – MCV & MCHC)

A. Microcytic Hypochromic Anaemia (Low MCV)

  •  Iron deficiency anaemia
  •  Thalassemia
  •  Sideroblastic anaemia
  •  Anaemia of chronic disease (sometimes)

B. Normocytic Normochromic Anaemia (Normal MCV)

  •  Acute blood loss
  •  Haemolytic anaemia
  •  Aplastic anaemia
  •  Anaemia of chronic disease
  •  Chronic kidney disease

C. Macrocytic Anaemia (High MCV)

  •  Megaloblastic anaemia
  •  Vitamin B12 deficiency
  •  Folic acid deficiency
  •  Non-megaloblastic
  •  Liver disease
  •  Alcoholism
  •  Hypothyroidism
  •  Drugs (e.g. methotrexate)

2. ETIOLOGICAL / PATHOPHYSIOLOGICAL CLASSIFICATION

A. Anaemia due to Blood Loss

  •  Acute (trauma, surgery)
  •  Chronic (peptic ulcer, hookworm, menorrhagia)

B. Anaemia due to Decreased RBC Production

  •  Iron deficiency
  •  Vitamin B12 / folate deficiency
  •  Aplastic anaemia
  •  Chronic kidney disease (↓ erythropoietin)
  •  Bone marrow infiltration (leukemia, malignancy)

C. Anaemia due to Increased RBC Destruction (Haemolytic Anaemia)

1. Intrinsic (Corpuscular)

  •  Hereditary spherocytosis
  •  Sickle cell disease
  •  Thalassemia
  •  G6PD deficiency

2. Extrinsic (Extracorpuscular)

  •  Autoimmune haemolytic anaemia
  •  Malaria
  •  Hypersplenism
  •  Mechanical (prosthetic valves)

3. CLINICAL CLASSIFICATION

A. Mild Anaemia

  •  Hb 10–12 g/dL

B. Moderate Anaemia

  •  Hb 7–9.9 g/dL

C. Severe Anaemia

  •  Hb <7 g/dL

If asked “classification of anaemia” without specification, start with morphological classification—it scores best in exams.”

Classification of Anaemia: Three Main Ways by Samwel Mikaye

More posts featuring Samwel Mikaye on Hemostasis Today.

Anaemia Classification Clinical Medicine Health Hematology Hemostasis Hemostasis News Hemostasis Today medical education Medical Exams Medicine Samwel Mikaye thrombosis
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