Claudio Laudani on Dual Versus Single Antiplatelet Therapy
Claudio Laudani, Cardiovascular Disease Fellow UNICT, Post-Doc Research Scholar UFHealth JAX, shared on LinkedIn:
”Dual antiplatelet therapy (DAPT) has long been the cornerstone of treatment after PCI, but advances in stent technology and pharmacology are reshaping how we balance ischemic protection and bleeding risk.
In this comprehensive review, we examine:
- The pharmacodynamic rationale of DAPT versus single antiplatelet therapy (SAPT), including differences among P2Y12 inhibitors.
- Clinical evidence comparing DAPT and SAPT strategies in chronic coronary syndrome and acute coronary syndrome patients undergoing PCI.
- The evolving role of early DAPT de-escalation and P2Y12 inhibitor monotherapy in optimizing net clinical benefit.
- Practical considerations for tailoring antiplatelet therapy based on individual ischemic and bleeding risk profiles, and areas where evidence remains limited.
Read more in our review article.”
Article: The pharmacology and clinical evidence for the use of dual versus single antiplatelet therapy
Authors: Claudio Laudani, Luis Ortega-Paz, Francesco Franchi, Fabiana Rollini, Ali Zgheib, Georges El Khoury, Maryam Farahmandsadr, Mohmmad Alawajneh, Marco Spagnolo, Giovanni Occhipinti, Davide Capodanno, Dominick J. Angiolillo
Stay updated on all scientific advances with Hemostasis Today.
-
Aug 9, 2026, 18:10James P. Crowley: How Turmeric and Green Tea May Affect Blood Sugar and Blood Pressure
-
Aug 9, 2026, 18:08Ahmed Alotaibi: How Many Lives Could Nationwide Prehospital Blood Access Potentially Save?
-
Aug 9, 2026, 18:06Are We Measuring What Matters Most in ITP? – ITP Australia and New Zealand
-
Aug 9, 2026, 18:03Mohamed Allaf: Aspirin and Clopidogrel Show Comparable Long-Term Survival After TAVI
-
Aug 9, 2026, 18:00Sangeeta Pathak: Delivering a Talk on Sustainable Blood Systems and Haemovigilance
-
Aug 9, 2026, 15:33Tareq Abadl: Kell System and Anti-K Alloimmunization
-
Aug 9, 2026, 15:16Antonella Cordoba: Emicizumab and the Evolving Landscape of Hemophilia A
-
Aug 9, 2026, 14:53Daniel Pereira Monteiro: Understanding Isoelectric Focusing in Hemoglobin Testing
-
Aug 9, 2026, 14:23Retheesh DasÖ‰ Edema Is a Sign, Not a Diagnosis