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DAPT De-escalation After PCI․ Where Do We Stand Today?
Davide Capodanno/LinkedIn
Jan 11, 2026, 03:54

DAPT De-escalation After PCI․ Where Do We Stand Today?

Davide Capodanno, Full Professor of Cardiology at the University of Catania, shared on X:

“ DAPT after PCI remains essential, but balancing ischemic protection and bleeding risk is challenging. Over the past decade, trials have supported DAPT de-escalation—via dose reduction, drug withdrawal, or switching agents—to reduce bleeding without compromising ischemic outcomes in selected patients. Evidence for escalation is more limited. We wrote this review to summarize current data and ongoing studies. ”

Title: Dual Antiplatelet Therapy Escalation and De-escalation

Authors: Antonio Greco, Giacinto Di Leo, Simone Finocchiaro, Antonino Imbesi, Davide Capodanno

Read full article here.

DAPT

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