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Fawaz AlOtaibi: Can AI Replace Contrast CTA for Vascular Screening?
Fawaz AlOtaibi/LinkedIn
Aug 16, 2026, 12:03

Fawaz AlOtaibi: Can AI Replace Contrast CTA for Vascular Screening?

Fawaz AlOtaibi, Neurocardiology and Cerebrovascular Fellow at Western University, shared a post on LinkedIn about a recent article by Jiahao Liao et al., published in International Journal of Stroke, adding:

”No dye, no second scan, just AI reading your vessels.

A new multicenter study (Int J Stroke) trained a deep learning model on approximately 3,700 patients to generate synthetic CTA images directly from plain non-contrast CT. No contrast dye, no additional scan, and no contrast-related risk.

The results: clinicians rated image quality 4.45 out of 5, with consistent performance across four external hospitals. When reading the AI-generated images blindly, they achieved 92.7 percent accuracy in distinguishing diseased from normal arteries, and around 91 percent accuracy in differentiating aneurysms from stenosis.

Not a replacement for real CTA, small vessels and hemorrhage-obscured aneurysms are still weak spots. But as a low-cost pre-screening/triage tool to flag who actually needs a contrast study, this is a compelling proof of concept.”

Title: AI-based synthetic CT angiography from non-contrast CT for cerebrovascular disease screening

Authors: Jiahao Liao, Bin Xu, Qianwen Zhang, Xin Wang, Xi Qiao, Kefei Chen, Jian Zhou, Jiansong Fan, Chuhan Xu, Hongxiang Wang, Yuhai Wang, Junsheng Chu, Jinxu Zhou

Fawaz AlOtaibi: Can AI Replace Contrast CTA for Vascular Screening?

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AI Bin Xu Chuhan Xu Fawaz AlOtaibi Health Hematology Hemostasis Hemostasis News Hemostasis Today Hongxiang Wang Jiahao Liao Jian Zhou Jiansong Fan Jinxu Zhou Junsheng Chu Kefei Chen Medicine Qianwen Zhang Vascular Screening Xi Qiao Xin Wang Yuhai Wang
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