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Federica Fogacci Presents The New ILEP Consensus Paper
Federica Fogacci/LinkedIn
Dec 7, 2025, 15:35

Federica Fogacci Presents The New ILEP Consensus Paper

Federica Fogacci, Young Fellow at European Atherosclerosis Society, shared on LinkedIn:

”Rethinking lipid management for stroke prevention – new ILEP Consensus Paper

Ischemic stroke accounts for ~66% of all strokes and is now the third leading cause of death worldwide – yet a large proportion of patients still have undiagnosed or undertreated lipid disorders, both before and after a cerebrovascular event.

Together with an amazing international team from the International Lipid Expert Panel (ILEP), in collaboration with the ESC Council on Stroke, we have just published a new consensus paper on lipid management for primary and secondary stroke prevention in Progress in Cardiovascular Diseases

What’s inside the paper?

  • Why dyslipidaemia (including LDL-C and Lp(a)) is a causal driver of ischaemic stroke
  • Clear, pragmatic LDL-C and apoB targets for patients at risk of stroke and for those with prior stroke/TIA
  • A strong message in favour of early, intensive and often combination lipid-lowering therapy (statins + ezetimibe ± PCSK9 inhibitors, bempedoic acid, inclisiran) to close the huge treatment gap in real-world practice
  • How to think about Lp(a), triglyceride-rich lipoproteins, and non-HDL-C in stroke prevention
  • The ILEP-SMILE framework: simple lifestyle “tips for the healthy cerebrum” to integrate pharmacological and non-pharmacological prevention

Our message is simple – and fully implementable in everyday practice:
“Lower is better, earlier is better, and longer is better” for LDL-C and overall lipid management in patients at risk of stroke and after stroke.
Even partial, consistent implementation of these principles could translate into fewer strokes and better long-term outcomes for our patients.”

Read the full article here.

Article: Lipid management for primary and secondary stroke prevention consensus paper of the International Lipid Expert Panel (ILEP)

Authors: Maciej Banach, Peter P. Toth, Hyo-Jeong Ahn, Agata Bielecka-Dabrowa, Arrigo F.G. Cicero, Adrian Covic, Mayank Dalakoti, Carlos Escobar, Federica Fogacci, Dan Gaita, Laura Gaita, Jacek Jóźwiak, Gustavs Latkovskis, Joanna Lewek, George Ntaios, Boguslaw Okopień, Ivan Pećin, Daniel Pella, Peter E. Penson, Marco Proietti, Gregory Y.H. Lip

Federica Fogacci Presents The New ILEP Consensus Paper

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Adrian Covic Agata Bielecka-Dabrowa Arrigo F.G. Cicero Boguslaw Okopień Carlos Escobar Dan Gaita Daniel Pella ESC Federica Fogacci George Ntaios Gregory Y.H. Lip Gustavs Latkovskis Health Hematology Hemostasis Hemostasis Today Hyo-Jeong Ahn ILEP Ischemic stroke Ivan Pećin Jacek Jóźwiak Joanna Lewek Laura Gaita Lipid Disorders Maciej Banach Marco Proietti Mayank Dalakoti Medicine Peter E. Penson Peter P. Toth thrombosis
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