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Frauke Swieringa: We Take a Deep Dive Into How Platelets Drive Thrombus Formation
Frauke Swieringa/LinkedIn
Sep 26, 2025, 13:50

Frauke Swieringa: We Take a Deep Dive Into How Platelets Drive Thrombus Formation

Frauke Swieringa, Senior scientist at Synapse BV, Maastricht, shared on LinkedIn:

”Excited to share the result of a great collaboration: our review “Platelet activation and signaling in thrombus formation” is now published in Blood.

In this review, we take a deep dive into how platelets drive thrombus formation ranging from classic platelet signaling pathways to surprising new players uncovered using phenotype information of 540 mouse genes.

We further emphasize how platelet responses change in venous, inflammatory, and infection-driven thrombosis, considering their interactions with the endothelium, leukocytes, and red blood cells.

A big “Thank you” to Alice Assinger! It was an honor and absolute pleasure to work with you and Johan Heemskerk on this exciting topic.”

Read the full article here.

Article: Platelet activation and signaling in thrombus formation

Authors: Frauke Swieringa, Alice Assinger, Johan Heemskerk

Frauke Swieringa: We Take a Deep Dive Into How Platelets Drive Thrombus Formation

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Alice Assinger Blood Endothelium Frauke Swieringa Health Hematology Hemostasis Hemostasis Today infection-driven thrombosis Johan Heemskerk Leukocytes Medicine platelets RBCs thrombosis
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