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Giuseppe Leone: Potential Causal Relationship between H. pylori and ITP
Aug 12, 2026, 05:22

Giuseppe Leone: Potential Causal Relationship between H. pylori and ITP

Giuseppe Leone, Editor in Chief on Mediterranean Journal of Hematology and Infectious Diseases, shared a post on LinkedIn about a recent article by Yuzhan Chen, published in Mediterranean Journal of Hematology and Infectious Diseases, adding:

“Observational studies have suggested a potential causal relationship between Helicobacter pylori (H. pylori) infection and Immune thrombocytopenia (ITP).

However, the evidence for causal inference remains contentious, and the underlying mechanisms require further investigation.

A Chinese group from Ningbo University conducted a Mendelian randomization (MR) analysis to assess this relationship, which is freely available online in the MJHID.”

Title: Causal relationship between helicobacter pylori antibodies and immune thrombocytopenia: a mendelian randomization study

Authors: Yuzhan Chen, Qitian Mu, Guifang Ouyang

Giuseppe Leone

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