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Heghine Khachatryan: Improving Long-Term Outcomes in PE Through Mechanical Thrombectomy
Heghine Khachatryan/LinkedIn
Jun 18, 2026, 14:01

Heghine Khachatryan: Improving Long-Term Outcomes in PE Through Mechanical Thrombectomy

Heghine Khachatryan, Editor-in-Chief of Hemostasis Today, Head of Hemophilia and Thrombosis Center at Yeolyan Hematology and Oncology Center, shared
Journal of Thrombosis and Haemostasis’ post on LinkedIn:

“Five-Year Survival After Large-Bore Mechanical Thrombectomy for Intermediate-High and High-Risk Pulmonary Embolism.

Pulmonary embolism remains one of the leading causes of cardiovascular mortality worldwide.

While systemic thrombolysis remains the standard reperfusion strategy for high-risk patients, catheter-based mechanical thrombectomy has emerged as a promising alternative, particularly in patients with contraindications to thrombolytic therapy or an elevated bleeding risk.

This study provides important long-term evidence, demonstrating favorable five-year survival following large-bore mechanical thrombectomy in patients with intermediate-high and high-risk pulmonary embolism.

The findings suggest that effective early thrombus removal may translate into durable clinical benefit beyond the acute phase of the disease.

The growing body of evidence supporting mechanical thrombectomy reflects a broader shift toward individualized, multidisciplinary management of pulmonary embolism, balancing efficacy, safety, bleeding risk, and long-term outcomes.

Further prospective studies are required to better define patient selection criteria, optimal treatment pathways, and the comparative effectiveness of catheter-based reperfusion strategies.”

Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Joshua Cornman-Homonoff et al, published in Journal of Thrombosis and Haemostasis, adding:

“Five-Year Survival After Large-Bore Mechanical Thrombectomy for Intermediate-High and High-Risk Pulmonary Embolism: A Single-Center Cohort.

In 100 consecutive PE patients treated with large-bore thrombectomy, five-year PE-related mortality was just 9 percent, with long-term survival largely driven by active malignancy and oxygenation needs at presentation.”

Title: Five-year survival after large-bore mechanical thrombectomy for intermediate-high and high-risk pulmonary embolism: a single-center cohort

Authors: Joshua Cornman-Homonoff, Matteo Conte, Akhil Khosla, Jeffrey Pollak, Hamid Mojibian

Heghine Khachatryan: Improving Long-Term Outcomes in PE Through Mechanical Thrombectomy

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Akhil Khosla Hamid Mojibian Health Heghine Khachatryan Hematology Hemostasis Hemostasis News Hemostasis Today Jeffrey Pollak Joshua Cornman-Homonoff Journal of Thrombosis and Haemostasis JTH Matteo Conte Mechanical thrombectomy Medicine Pulmonary embolism
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