Hortense Triniac Shares PhD Research: How Cortical Neurons Process and Activate tPA
Hortense Triniac, Postdoctoral researcher at Versiti Blood Research Institute, shared a post on LinkedIn:
“I’m excited to share our latest publication, part of my PhD work at PhIND – BB@C (Cyceron, Université de Caen, France), on the neuronal processing of tPA — showing how cortical neurons are able to cleave single-chain tPA into its two-chain isoform at their cell surface.
Read the full paper here.
Many thanks to my co-authors and supervisors Simon Lebatard, Valerie Roussel, Charlotte Lechevallier, Laurent Lebouvier, Denis Vivien, and Benoît Roussel.”
Title: Neuronal conversion of single-chain tissue-type plasminogen activator into its two-chain form: implications in neurodevelopment, learning, and memory
Authors: Hortense Triniac, Simon Lebatard, Valerie Roussel, Charlotte Lechevallier, Laurent Lebouvier, Denis Vivien, Benoit D. Roussel
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