Platelet Dependent Protection Against Bacterial Pneumonia – JTH
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about recent article by Shuju Feng, adding:
“Non hemostatic platelet dependent protection against murine bacterial pneumonia
In mice challenged with aerosolized Pseudomonas aeruginosa or Streptococcus pneumoniae, thrombocytopenia and aspirin treatment both increased mortality and pulmonary pathogen burden.
Impaired antimicrobial defense appeared at platelet counts still sufficient for hemostasis, with pulmonary hemorrhage only in severe thrombocytopenia, separating the platelet’s innate immune role from its hemostatic one.”
Title: Nonhemostatic platelet-dependent protection against murine bacterial pneumonia
Authors: Shuju Feng, Vikram V. Kulkarni, Jezreel Pantaleón García, Valentina Mani Jacques, Hani Lee, Caleb J. Kroll, James Feng, Andrea M. Mastro, Yongxing Wang, Scott E. Evans, Michael H. Kroll, Vahid Afshar Kharghan
Stay updated on all scientific advances with Hemostasis Today.
-
Nov 8, 2026, 12:22Marc Carrier: Advancing Catheter-Related Thrombosis Prevention Through Factor XI Inhibition
-
Nov 8, 2026, 11:56Why Genetic Predisposition Does Not Always Lead to Thrombosis – Stork Genetics
-
Nov 8, 2026, 11:45Sher-Lu Pai: Investigating Intracardiac Thrombosis and Its Management in Liver Transplantation
-
Nov 8, 2026, 11:25Mehmet Cilingiroglu: Navigating Anticoagulation Choices in Acute Coronary Syndrome PCI
-
Nov 8, 2026, 07:16Gilberto de lima Lopes Junior: The Cardiovascular Consequences of Cancer in Younger Patients
-
Nov 8, 2026, 06:51Haney Mallemat: Key Principles and Pitfalls of LVAD Emergencies
-
Nov 8, 2026, 06:31Maria Omer: Clinical Recognition and Management of Cavernous Sinus Thrombosis
-
Nov 8, 2026, 06:16Natasha Jolakoski: University of New Mexico Hospital Promotes PGY-2 Thrombosis and Hemostasis Management Pharmacy Residency
-
Nov 8, 2026, 05:47Safaa Hilal: POCUS in the Evaluation of Perioperative Troponin Elevation