Mary Cushman: Covering Associations of Antiphospholipid Antibodies with Stroke
Mary Cushman, University Distinguished Professor and Vice Chair at the University of Vermont, shared a post on LinkedIn, about a recent article she and her colleagues co-authored, published in Stroke journal, adding:
“New manuscript out in Stroke journal covering associations of antiphospholipid antibodies with stroke.
Great to work with Behnood Bikdeli’s group on this!
In 52 studies:
- Pooled prevalence of seropositivity for any aPL in >9000 people with ischemic stroke was 19.1%. That’s high!
- aPL seropositivity was associated with 2.93-fold increased risk of first ischemic stroke (43 studies, 19 097 patients.
- Strongest association was for lupus anticoagulant or, 6.69 )95% CI, 2.94–15.2).”
Title: Prevalence and Clinical Relevance of Antiphospholipid Antibodies in Ischemic Stroke: A Systematic Review and Meta-Analysis
Authors: Nathan W. Watson, Syed Bukhari, Sina Rashedi, Mariana Pfeferman, Francisco Ujueta, Bassil Bacare, Brittany N. Weber, Mehrdad Zarghami, Yogendra Kanthi, Eric A. Secemsky, Jean M. Connors, Geoffrey D. Barnes, Sacha Uljon, Samuel Z. Goldhaber, Jeffrey I. Weitz, Karen H. Costenbader, Harlan M. Krumholz, Gregory Piazza, Mary Cushman, Christopher D. Anderson, Mitchell S. V. Elkind, Behnood Bikdeli
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