Mud Alvi: The Interaction Between LV Injury and Cryptogenic Stroke
Mud Alvi, Professor and Vice Chair of Neurology at West Virginia University, shared a post on LinkedIn about a recent article he and his colleagues co-authored, adding:
“I’m proud to share a recent publication from a truly outstanding multicenter collaboration in American Heart Association Stroke journal.
This project brought together investigators across 27 U.S. sites including WVU Rockefeller Neuroscience Institute as part of the Cardiac Abnormalities in Stroke Prevention and Recurrence (CASPR) cohort.
This effort was led by Jim Siegler and Richa Sharma. It was a privilege to work alongside them in advancing secondary stroke prevention through collaboration.
Our study examined the interaction between left ventricular (LV) injury and cryptogenic stroke.
We found a striking treatment interaction: among patients with LV injury, anticoagulation was associated with substantially lower risk of recurrent stroke, major bleeding, or death — a pattern not seen in those without LV injury.
These findings should lead to next generation of randomized trials.
Grateful for the teamwork behind this work — and excited for what comes next.”
Title: Recurrent Stroke in Patients With Cryptogenic Stroke and Left Ventricular Injury: The Cardiac Abnormalities in Stroke Prevention and Recurrence (CASPR) Study
Authors: Richa Sharma, Katelyn F. McNamara, Elena Badillo Goicoechea, Anna Bowman, Russell Van Coevering, Lucia Chen, Mary Penckofer, Eesha Singh, Deborah Kerrigan, Hassan Aboul-Nour, Fadi Nahab, Patrick Glover, Balaji Krishnaiah, Shadi Yaghi, Farid Khasiyev, Christina Lineback, Emiliya Melkumova, Collin Culbertson, Thanh N. Nguyen, Sean L. Thompson, Dinesh Jillella, Jean-Philippe Auguste Daniell, Yasmin Aziz, Muhammad Alvi, Franziska Herpich, Mahan Shahrivari, Rafail A. Chionatos, Cheran Elangovan, Jieun Kang, Alicia Zha, Mudassir Farooqui, Aaron Rothstein, Farhan Khan, Matthew Smith, Samantha Brown, Ahmad Abu Qdais, David S. Liebeskind, Nandini Abburi, Stefano Rozental, Simona Nedelcu, Jesse M. Thon, Christoph Stretz, Neeharika Thottempudi, Wenzheng Yu, Kelsey Eklund, Guillermo Linares, Adam de Havenon, James E. Siegler
Read the Full Article on Stroke
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