Pablo Corral: “The lower, The better” Applies to The Brain Too
Pablo Corral, Pharmacology Professor at FASTA University, Past President of Argentine Lipid Society, posted on LinkedIn:
”Lower LDL-C, Lower Risk – Safely
New analysis from FOURIER & FOURIER-OLE (Monguillon et al., Circulation 2025):
In patients with prior ischemic stroke, achieving LDL-C <40 mg/dL led to a continuous reduction in MACE and recurrent stroke, without any increase in hemorrhagic stroke.
- 5,291 stroke patients
- Follow-up up to 7 years
- Stepwise reduction in cardiovascular and ischemic events with lower LDL-C
- Hemorrhagic strokes: rare and unrelated to LDL-C
Conclusion: Very low LDL-C levels (<40 mg/dL) are both effective and safe for secondary prevention after stroke – confirming that “the lower, the better” also applies to the brain.”
Read the full article here.
Title: Efficacy and Safety of Very Low Achieved LDL-Cholesterol in Patients with Prior Ischemic Stroke
Authors: Victorien Monguillon, Peter Kelly, Michelle L. O’Donoghue, Jeong-Gun Park, Erin A. Bohula, Jeffrey L. Saver, Dan Atar, Anthony C. Keech, Peter S. Sever, Huei Wang, Gabriel Paiva da Silva Lima, Marc S. Sabatine, Robert P. Giugliano
Stay updated with Hemostasis Today.
-
Nov 8, 2025, 05:31Phenotyping of Human Platelets by Daisie Yates
-
Nov 8, 2025, 04:35Inaugural Women In Hematology US Focus Meeting 2025 Officially Commenced
-
Nov 8, 2025, 01:40Mikhail Fominykh: What I Read This Week
-
Nov 8, 2025, 01:40Shubham Khandve: Cell and Gene Therapy is No Longer the Future
-
Nov 8, 2025, 01:39World Federation of Hemophilia: Hemophilia Care is Evolving
-
Nov 8, 2025, 01:38Muhammad Awidi – Choking Growth One Puff at a Time: How Tobacco is Strangling Jordan’s Economy
-
Nov 8, 2025, 01:38Abdul Mannan Inside the Diagnostic Maze of Atypical CML
-
Nov 8, 2025, 01:37Steven Murphy Discusses Peptides in Orthobiologic Medicine at AMSKU 2025
-
Nov 8, 2025, 01:37Cellfie of the Day: Classic Gaucher Cells Under the Microscope