Why Pediatric ROTEM Needs Race-Specific Reference Ranges?
Vera Ignjatovic, Founder and Managing Director of Ignis Innovations Pty Ltd, shared a post by Journal of Thrombosis and Haemostasis (JTH) on LinkedIn:
”Here is the link to our paper describing the age and race-specific association of fibrinogen and Rotational Thromboelastometry (ROTEM) parameters in a diverse pediatric population.
Inclusion of a diverse population in establishing race-specific pediatric RIs has clinical and public health relevance for a more accurate diagnosis and personalized treatment.
Thank you, Marium Malik, Maha Al-Ghafry, Maribel Lema, Vijay Nandi, Linda Shore-Lesserson, and Suchitra S. Acharya for making this study possible. I am privileged to have worked with you in the late stages of this study.”
Quoting Journal of Thrombosis and Haemostasis (JTH)’s post:
”Association of fibrinogen and ROTEM parameters with age and race in a diverse pediatric population: a single-center study
By Marium Malik, Maha Al-Ghafry, Maribel Lema, Vijay Nandi, Vera Ignjatović, Linda Shore-Lesserson, and Suchitra S. Acharya
• Pediatric reference ranges for Rotational Thromboelastometry (ROTEM) – a whole-blood coagulation assay – are limited and rarely account for racial diversity.
• In 105 racially diverse children (1–21 years), investigators analyzed how age and race affect fibrinogen and ROTEM variables (EXTEM, INTEM, and FIBTEM).
• Fibrinogen and FIBTEM clot strength increased with age. Among Black/African American participants, rising age correlated with shorter clot times and stronger clot firmness, suggesting a prothrombotic hemostatic profile. This underscores the need for race-specific pediatric reference intervals for personalized coagulation assessment.
Read the article here.”
Title: Association of fibrinogen and Rotational Thromboelastometry (ROTEM) parameters with age and race in a diverse pediatric population: a single-center study
Authors: Marium Malik, Maha Al-Ghafry, Maribel Lema, Vijay Nandi, Vera Ignjatovic, Linda Shore-Lesserson, Suchitra S. Acharya
Stay updated with Hemostasis Today.
-
Jan 9, 2026, 12:17Louise St Germain Bannon Invites You to Self-Nominate for the ISTH Council
-
Jan 9, 2026, 09:25Emma Groarke Shares A Comprehensive Review on VEXAS Syndrome
-
Jan 9, 2026, 09:13Anirban Sen Gupta Presents PlateChek
-
Jan 9, 2026, 08:58Oscar Pena Shares KDIGO 2026 Update: 5 Critical Changes for Anemia in CKD Management
-
Jan 9, 2026, 07:38Bartosz Hudzik on Subacute Coronary Occlusions: Navigating the Gray Zone in CAD Care
-
Jan 9, 2026, 07:27Gregory Piazza on The Role of D-Dimer in VTE Evaluation
-
Jan 9, 2026, 07:19Emmanuel J Favaloro Shares the 1st Article in a VWD Series Marking the 100-Year Anniversary
-
Jan 9, 2026, 07:07Taylor Robichaux on Recombinant ADAMTS13 Therapy in cTTP
-
Jan 9, 2026, 06:25Sara Ng: VTE Continues to Plague Modern Oncology