Sergio Emanuel Kaiser: A Whole New Array of Potent Oral PCSK9 Inhibitors
Sergio Emanuel Kaiser, Coordinator at UERJ – Discipline of Clinical and Experimental Pathophysiology, Associate Professor of Medicine at Rio de Janeiro State University, shared a post on LinkedIn about a recent article by Rick B. Vega, published in Circulation, adding:
“Exciting!
A whole new array of potent oral PCSK9 inhibitors is underway!
An 80% reduction of LDLc with the highest dose when associated with rosuvastatin 20 mg!”
Title: Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naive Patients
Authors: Rick B. Vega, Gavin O’Mahony, April M. Barbour, Hongtao Yu, Jane Knöchel, Johan Brengdahl, Thomas Hochdörfer, Linnéa Bergenholm, Eva Töppner Carlsson, Andrea Ahnmark, Christina Rye Underwood, Anna Rudvik, Debra Carter, Johanna Laru, Aspen Gutgsell, Lee Twaddle, Pavlo Garkaviy, Anna Bogstedt, Eva Hurt-Camejo, Tasso Miliotis, Maria Ryaboshapkina, Andrease Hober, Brian Hubbard, Michael Serrano-Wu, Virendar Kaushik, Stefan Geschwindner, Michael C. McCarthy, Daniel Lindén, Jaya B. Rosenmeier
Stay updated on all scientific advances with Hemostasis Today.
-
May 25, 2026, 07:34Wolfgang Miesbach: The Maastricht Bleeding Cohort and The High Prevalence of BDUC in Women
-
May 25, 2026, 07:31Maya Brown-Zimmerman: Bridging Patient Experience and Genetic Counseling in Marfan Syndrome
-
May 25, 2026, 05:25Abdullah Mohsin: Automated Detection of DVT Using Deep Learning and Doppler Ultrasound
-
May 25, 2026, 05:07The Dual Role of PAI-1 Mutations in Bleeding and Thrombotic Disorders – ICHCC
-
May 25, 2026, 05:04Fibrinogen αC Domain Lysines Drive Plasminogen Binding and Plasmin Generation – JTH
-
May 25, 2026, 04:50Gülşah Türkoğlu: An Encouraging Momentum Around the Adoption of Resolutions on Stroke Care at WHA79
-
May 25, 2026, 04:47Krishnakant Prasad: A Quick Clinical Review of Renal Papillary Necrosis
-
May 25, 2026, 04:40Rajiv Kumar Jain: World Health Assembly Adopts First-Ever Global Resolution on Stroke Prevention and Care
-
May 25, 2026, 04:23Sarfraz Ahmad: Diagnostic and Therapeutic Challenges in ICA Aneurysm Presenting With Epistaxis