Sergio Emanuel Kaiser: A Whole New Array of Potent Oral PCSK9 Inhibitors
Sergio Emanuel Kaiser, Coordinator at UERJ – Discipline of Clinical and Experimental Pathophysiology, Associate Professor of Medicine at Rio de Janeiro State University, shared a post on LinkedIn about a recent article by Rick B. Vega, published in Circulation, adding:
“Exciting!
A whole new array of potent oral PCSK9 inhibitors is underway!
An 80% reduction of LDLc with the highest dose when associated with rosuvastatin 20 mg!”
Title: Laroprovstat, the First Oral Small-Molecule PCSK9 Inhibitor for the Treatment of Hypercholesterolemia: Results From a Randomized, Single-Blind, Placebo-Controlled Phase 1 Trial in Treatment-Naive Patients
Authors: Rick B. Vega, Gavin O’Mahony, April M. Barbour, Hongtao Yu, Jane Knöchel, Johan Brengdahl, Thomas Hochdörfer, Linnéa Bergenholm, Eva Töppner Carlsson, Andrea Ahnmark, Christina Rye Underwood, Anna Rudvik, Debra Carter, Johanna Laru, Aspen Gutgsell, Lee Twaddle, Pavlo Garkaviy, Anna Bogstedt, Eva Hurt-Camejo, Tasso Miliotis, Maria Ryaboshapkina, Andrease Hober, Brian Hubbard, Michael Serrano-Wu, Virendar Kaushik, Stefan Geschwindner, Michael C. McCarthy, Daniel Lindén, Jaya B. Rosenmeier
Stay updated on all scientific advances with Hemostasis Today.
-
Aug 31, 2026, 05:35Does LDL Cholesterol Influence VTE Risk? – Ordo Fraterna Fibonacci
-
Aug 31, 2026, 05:19Tania Ahuja: Apixaban in Abdominal Transplant Patients
-
Aug 31, 2026, 04:28Reza Hafidz Irawan։ Automated Antibody Titration With Erytra Eflexis
-
Aug 31, 2026, 04:17Safa Chenganath: Stenosis vs Thrombosis – Hemodialysis Vascular Access
-
Aug 30, 2026, 17:13J. Meireles-Brandao: Hypertension, Inflammation and Lipoprotein Disease
-
Aug 30, 2026, 17:10Hugh Nguyen: Leading the New Era of Blood Services Across Asia Pacific
-
Aug 30, 2026, 17:09Transforming Childhood Through Access to Hemophilia Treatment – World Federation of Hemophilia
-
Aug 30, 2026, 17:07Raj Bharath: Connecting Clinicians and Researchers to Advance Transfusion Medicine
-
Aug 30, 2026, 17:04Rana Al Hrout: Free FRCPath Haematology Part 1 Exam Preparation Session