Shadi Tabibian: Understanding Thrombotic Risk in Rare Bleeding Disorders
Shadi Tabibian, Deputy of Research at Blood Diseases Research Centers in Iran University of Medical Sciences, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Thrombosis Journal, adding:
“I am pleased to share our newly published article in Thrombosis Journal:
‘Thrombosis in rare bleeding disorders: a bleeding phenotype does not fully preclude thrombotic risk.’
Thrombosis in patients with rare bleeding disorders is uncommon, but clinically important and potentially life-threatening.
In our cohort of 1,251 patients, 12 individuals (0.96 percent) experienced imaging-confirmed thrombosis.
All events were venous and occurred mainly in high-risk clinical settings, including pregnancy, surgery, infection, and exposure to replacement therapy.
The key message is clear: having a bleeding disorder does not eliminate thrombotic risk.
Recognizing prothrombotic triggers and carefully individualizing anticoagulation and replacement therapy are essential for safe patient management.
I am grateful to my co-authors and all the patients and clinical teams who contributed to this work.”
Title: Thrombosis in rare bleeding disorders: a bleeding phenotype does not fully preclude thrombotic risk- frequency, clinical contexts, and management in a large Iranian cohort
Authors: Majid Naderi, Saeedeh Yaghoubi, Sina Rajaee, Ilia Mirzaei, Shadi Tabibian

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