Sheharyar Raza et al on Factor XIII Supplementation in Postpartum Hemorrhage
Sheharyar Raza, Transfusion Medicine Specialist and Data Scientist at University Health Network, shared on LinkedIn:
“Clots are bricks (platelets) and cement (fibrin). When we can’t maintain fibrin, severe bleeding can ensue. This is a major driver of postpartum hemorrhage, the leading cause of maternal death during childbirth globally.
In a new article, co-authors Jeremy Jacobs et al critically review the pathophysiology of postpartum hemorrhage, emphasizing fibrin breakdown and the potential role of clotting Factor XIII therapy in cases of severe, refractory bleeding.
Read open access.”
Title: Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation
Authors: Jeremy W. Jacobs, Elizabeth A. Abels, Brian D. Adkins, Garrett S. Booth, Victoria Costa, Sheharyar Raza, Michelle Simon, Jennifer S. Woo, Allison P. Wheeler
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