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Shirley D’Sa: Vitamin B6 Offers a New Clue in the POEMS Syndrome Puzzle
Jul 15, 2026, 13:44

Shirley D’Sa: Vitamin B6 Offers a New Clue in the POEMS Syndrome Puzzle

Shirley D’Sa, Professor of Haematology at United KingdomUnited Kingdom, shared on LinkedIn about a recent article she and her colleagues co-authored, published in Journal of Neurology, Neurosurgery and Psychiatry, adding:

”A long-standing puzzle.

A new piece of the answer.

For decades, the mechanisms underlying nerve damage in POEMS syndrome have remained elusive.

Our newly published study investigates the role of vitamin B6, providing a fresh perspective on the biology of this complex disease.

Science moves forward one step at a time—but occasionally those steps change the direction of travel.

We hope this is one of them.”

Title: Acquired vitamin B6 deficiency in POEMS: a marker of disease activity and cause of neuropathy?

Authors: Oliver Tomkins, Simon Alexander Samuel Pope, Youssef Khalil, Shiwen Koay, Jahanzaib Khwaja, Jonathan Sive, Shirley D’Sa, Philippa B. Mills, Peter T. Clayton, Michael P. Lunn

Shirley D’Sa: Vitamin B6 Offers a New Clue in the POEMS Syndrome Puzzle

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