Sophia Delicou: Importance of Assessing Hemoglobin Functional Capacity Rather Than Total Levels
Sophia Delicou, Clinical Hematologist and Head of the Thalassemia and Sickle Cell Unit at Hippocration General Hospital, Athens, posted on LinkedIn:
”I am pleased to share our recent publication ‘Functional Anaemia in Homozygous δβ-Thalassaemia Lepore Identified via HPLC’, published in the International Internal Medicine Journal.
This work presents a clinical case of homozygous δβ-thalassaemia Lepore, highlighting the importance of assessing the functional capacity of hemoglobin rather than relying solely on total hemoglobin levels.
Despite elevated HbF levels, its increased oxygen affinity may compromise effective tissue oxygen delivery, resulting in a state of functional anemia with relevant clinical implications.
These findings are particularly meaningful in the context of contemporary therapeutic strategies that aim to increase HbF levels.
I would like to thank my co-authors and collaborators for their valuable contributions and collaboration throughout this work.”
Title: Functional Anaemia in Homozygous δβ-Thalassaemia Lepore Identified via HPLC
Authors: Sophia Delicou1, Sotirios Bristogiannis, Katerina Xydaki, Maria Moraki, Maria Kozanitou
Read the Full Article on Opast.
Sophia Delicou/LinkedInStay updated with Hemostasis Today.
-
Apr 16, 2026, 04:03Platelet DGD – A Common But Underdiagnosed Bleeding Disorder – RPTH
-
Apr 16, 2026, 03:51William Wallace: How Vitamin B12 Is Being Absorbed?
-
Apr 16, 2026, 03:36Santagata Davide: Atypical Vascular Events Revealing Underlying Clonal Autoinflammation
-
Apr 16, 2026, 03:35Iron Deficiency in Women During Reproductive Years – ASH
-
Apr 16, 2026, 03:33Abdallah Othman: Overview of Coronary Arterial Anatomy and Its Clinical Implications
-
Apr 16, 2026, 03:14Laura Girardi: A Survey Study on the Management of Incidental Pulmonary Embolism in Patients with Cancer
-
Apr 16, 2026, 03:10Folusho Adeosun: Your 30-Minute Plan for SCD Emergencies
-
Apr 16, 2026, 02:57Charlie Windri: CAC as the Missing Link in Lp(a) Risk
-
Apr 15, 2026, 21:27Satish Bondala: Blood Bank and Transfusion Services – The Lifeline of Hospitals