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Late-Window Stroke: Hyperglycemia Doesn’t Alter EVT Benefit
The International Journal of Stroke/X
Jul 5, 2025, 17:38

Late-Window Stroke: Hyperglycemia Doesn’t Alter EVT Benefit

The International Journal of Stroke recently shared a post on X:

”Just Accepted! Study in those with acute ischemic stroke and large vessel occlusion of the anterior circulation. Results show hyperglycaemia does not modify the efficacy of endovascular therapy in the late time window.”

Read the full article here.

Hyperglycemia has long been the unwelcome guest at the stroke table, often associated with worse outcomes and suspected of meddling with treatment effects—especially in early endovascular therapy (EVT).

Naturally, one might expect it to play a similarly disruptive role in patients treated in the late window (6 to 24 hours after symptom onset or last known well).

But in the study of anterior circulation large vessel occlusion stroke, Clemens Kersten et al. showed that hyperglycemia had surprisingly little to say.

Regardless of admission glucose levels, the benefit of EVT remained unchanged.

In conclusion, no evidence that admission glucose or hyperglycemia modifies the benefit of EVT in this population, suggesting EVT efficacy remains consistent across a range of glucose levels in the late window setting.

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endovascular therapy EVT Health Hematology Hemostasis Today Hyperglycemia Ischemic stroke Late Window Stroke Medicine Sage Journals stroke The International Journal of Stroke
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