Hemostasis Today
NewsFeed
Headlines Hematology Health Medicine VTE ASH Plasma Donation
August, 2026
August 2026
M T W T F S S
 12
3456789
10111213141516
17181920212223
24252627282930
31  
David Smadja: Molecular Determinants of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes
David Smadja/Bruno Guglielminetti's LinkedIn
Sep 8, 2025, 06:12

David Smadja: Molecular Determinants of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes

David Smadja, Professor of Hematology (PU-PH) at University of Paris Cité, European Georges Pompidou Hospital, shared on LinkedIn:

”I am pleased to contribute to this international study led by the team of David-Alexandre Trégouët (first author: Gaëlle Munsch), which explores the molecular determinants of the recurrence of venous thromboembolism (VTE).

Through genomic analysis of more than 6,300 patients (including 1,775 recurrences), 28 molecular markers were identified that were associated with the risk of recurrence, revealing that the genetic architecture of this risk varies according to the type of initial event (deep vein thrombosis, pulmonary embolism, induced or not).

These results open up prospects for more personalized medicine, in order to better predict recurrence and adapt the duration of anticoagulant treatments.

This is an important step towards targeted prevention strategies and possible new therapeutic levers.

Reference: Munsch G. et al., Blood 2025 [DOI: 10.1182/blood.2024027879]”

Read the full article here.

Article: Molecular Determinants of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes

Authors: Gaëlle Munsch, Florian Thibord, Ohanna C. Bezerra, Jennifer A. Brody, Astrid van Hylckama Vlieg, Lenaick Gourhant, Ming-Huei Chen, Floriane Samaria, Marine Germain, Ilana Caro, Pierre Suchon, Robert Olaso, Kerri L. Wiggins, Noémie Saut, Céline Besse, Louisa Goumidi, Delphine Bacq, Laura B. Harrington, Anne Boland, Joseph Emmerich, David M. Smadja, Catherine A. Lemarie, Sven Danckwardt, Stephanie Debette, Jean-François Deleuze, Hélène Jacqmin-Gadda, Marc A. Rodger, France Gagnon, Frits R. Rosendaal, Andrew D. Johnson, Nicholas L. Smith, Francis Couturaud, Pierre-Emmanuel Morange, David-Alexandre Tregouet

David Smadja: Molecular Determinants of Thrombosis Recurrence Risk Across Venous Thromboembolism Subtypes

Stay informed on all scientific advances in the field of thrombosis with Hemostasis Today.

Andrew D. Johnson Anne Boland ASH Astrid van Hylckama Vlieg Blood Catherine A Lemarie Céline Besse David M. Smadja David-Alexandre Tregouet deep vein thrombosis Delphine Bacq Florian Thibord Floriane Samaria France Gagnon Francis Couturaud Frits R Rosendaal Gaëlle Munsch Health Hélène Jacqmin-Gadda Hematology Hemostasis Hemostasis Today Ilana Caro Jean-François Deleuze Jennifer A Brody Joseph Emmerich Kerri L Wiggins Laura B Harrington Lenaick Gourhant Louisa Goumidi Marc A Rodger Marine Germain Medicine Ming-Huei Chen Nicholas L Smith Noémie Saut Ohanna C Bezerra Pierre Suchon Pierre-Emmanuel Morange Pulmonary embolism Robert Olaso Stephanie Debette Sven Danckwardt thrombosis venous thromboembolism VTE
NewsFeed