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Nicolas Gendron on TITAN’s Recent Study: Insights on Managing Pregnancy in Antithrombin Deficiency
Aug 4, 2025, 16:13

Nicolas Gendron on TITAN’s Recent Study: Insights on Managing Pregnancy in Antithrombin Deficiency

Nicolas Gendron, Research Fellow, Hematologist at Boston Children’s Hospital, shared a proud post on LinkedIn:

‘Pregnancy and Antithrombine Deficiency

We are very pleased to announce the online publication of our French recommendations on the management of pregnancy in women with congenital antithrombin deficiency (ATD), published in Thromb Haemost (Thrombosis Haemostasis Journal).

Congenital antithrombin deficiency is a rare condition but is associated with a major thromboembolic risk, particularly in the context of pregnancy.
Given the limited literature and heterogeneous international recommendations, the Thrombosis, Anticoagulants, and Antiplatelet Agents (TITAN) group of the French Society for Thrombosis and Hemostasis (SFTH) conducted an in-depth review of the literature in order to propose concrete elements to aid decision-making.

These proposals address:

  • The indication and dosage regimen for anticoagulants
  • Relevant biological monitoring
  • The role of antithrombin concentrates during and at the end of pregnancy
  • The crucial importance of multidisciplinary coordination between hematologists, obstetricians, and anesthesiologists.

Read the full article here.

Congratulations to all the co-authors for this collective work! Special thanks to Laurent for leading the project.
Mauge Laetitia, Hugo Madar, Julie Carré, Mathieu Fiore, Christine Mouton, Valérie Proulle, Suchon Pierre, Nathalie Trillot, Thomas Lechat, Loïc Sentilhes and Laurent Macchi.”

Article: How to Manage Venous Thromboembolism Risk during Pregnancy in Patients with Inherited Antithrombin Deficiency?

Authors: Laetitia Mauge , Hugo Madar, Julie Carré, Mathieu Fiore, Nicolas Gendron, Christine Mouton, Valérie Proulle, Pierre Suchon, Nathalie Trillot, Thomas Lechat, Loïc Sentilhes, Laurent Macchi, On behalf of the TITAN group of the French Society of Thrombosis and Haemostasis (SFTH)

Nicolas Gendron on TITAN’s Recent Study: Insights on Managing Pregnancy in Antithrombin Deficiency

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