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Christopher Cannon: Clopidogrel Monotherapy is Superior to Aspirin Monotherapy for MACCE Prevention
Sep 23, 2025, 06:41

Christopher Cannon: Clopidogrel Monotherapy is Superior to Aspirin Monotherapy for MACCE Prevention

 

Christopher Cannon, Cardiologist at Brigham and Women’s Hospital, Editor-in-Chief of Harvard Heart Letter, posted on LinkedIn:

”New meta-analysis: “clopidogrel monotherapy is superior to aspirin monotherapy for MACCE prevention with no increase in the risk of bleeding.” The CAPRIE  trial had it right 20 years ago.
I have been shifting more and more of my patients to long-term clopidogrel in place of ASA.”

Read the full article here.

Title: Clopidogrel versus aspirin for secondary prevention of coronary artery disease: a systematic review and individual patient data meta-analysis

Authors: Marco Valgimigli, Ki Hong Choi, Daniele Giacoppo, Felice Gragnano, Takeshi Kimura, Hirotoshi Watanabe, Hyo-Soo Kim, Jeehoon Kang, Kyung Woo   Park, Alf-Åge Pettersen, Mark Woodward, Deepak L Bhatt, Paolo Calabrò, Dominick J Angiolillo, Roxana Mehran, Young Bin Song, Joo-Yong Hahn

 

Clopidogrel

 

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