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Ilja Oomen on Immune Tolerance Induction Failure and Hemophilia A
Oct 29, 2025, 01:36

Ilja Oomen on Immune Tolerance Induction Failure and Hemophilia A

Ilja Oomen, PhD candidate in Pediatric Hematology at AMC – Academic Medical Center, shared on LinkedIn:

”Happy to share!

Our latest article on genetic variants that predict immune tolerance induction failure in people with severe hemophilia A has been published in RPTH Journal.

Over 10 years of hard work with our International GO-ITI steering group with collaborating centers in Brazil, Canada, Germany, Italy and the Netherlands, has resulted in this interesting article.

Working towards a better prediction of the chance of ITI succes (or risk of ITI failure) before starting this intensive treatment!

Many thanks to our fellow researchers for their enthusiasm and dedication.”

Read the full article in RPTH.

Article: Large deletions in the F8 gene predict immune tolerance induction failure in people with severe hemophilia A

Authors: Ilja Oomen, Amal Abdi, Linda Broer, Ricardo M. Camelo, Fábia M.R.A. Callado, Luany E.M. Carvalho, Ilenia L. Calcaterra, Manuel Carcao, Giancarlo Castaman, Jeroen C.J. Eikenboom, Kathelijn Fischer, Vivian K.B. Franco, Judy Geissler, Taco W. Kuijpers, Frank W.G. Leebeek, David Lillicrap, Cláudia S. Lorenzato, Maria Elisa Mancuso, Davide Matino, Matteo N.D. Di Minno, Aomei Mo, Alex B. Mohseny, Sietse Q. Nagelkerke, Johannes Oldenburg, Suely Meireles Rezende, Georges-Etienne Rivard, Natalia Rydz, Saskia E.M. Schols, Michael W.T. Tanck, Jan Voorberg, Karin Fijnvandraat, Samantha C. Gouw on behalf of the International GO-ITI Steering Group

Ilja Oomen on Immune Tolerance Induction Failure and Hemophilia A

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