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Matteo Foschi Presents The New Expert Guidance on Minor Ischemic Stroke
Matteo Foschi/X
Dec 12, 2025, 09:22

Matteo Foschi Presents The New Expert Guidance on Minor Ischemic Stroke

Matteo Foschi, Neurologist at Azienda USL della Romagna, shared on LinkedIn:

”Thrilled to share our new Expert Guidance on the acute management of minor ischemic stroke!

Honored to have co-led this work with an outstanding international team of stroke leaders, now published in Stroke (American Heart Association).

Federico De Santis, Lucio D’Anna, Urs Fischer, Else Charlotte Sandset, Thanh Nguyen, Ahmed Nasreldein, Octavio Marques Pontes-Neto, Tsivgoulis Georgios, Pooja Khatri, Shelagh Coutts, Guillaume Turc, Simona Sacco

Minor ischemic strokes may appear “mild,” but up to 30% of patients develop disability within 90 days — a reminder that minor does not mean benign.

Our guidance provides a pragmatic, scenario-based framework to support clinicians in navigating some of the most controversial areas in acute stroke care:

  • Disabling vs nondisabling minor stroke
  • Role of IV thrombolysis and dual antiplatelet therapy
  • Early anticoagulation in cardioembolic minor stroke
  • When (and whether) to perform thrombectomy in low NIHSS with LVO
  • Managing rapidly improving symptoms
  • Post-reperfusion antithrombotic strategies
  • Considerations for low-resource settings

This document aims to translate complex evidence into clear, actionable decision pathways, highlighting where we do have robust data — and where future trials are urgently needed.

A huge thank you to all coauthors and collaborators worldwide for their expertise, energy, and commitment

Open access article available now.

Proud to contribute to improving global stroke care and to stimulate the next generation of research in this challenging field.”

Read the full article here.

Article: Acute Treatment of Disabling and Nondisabling Minor Ischemic Stroke: Expert Guidance for Clinicians

Authors: Federico De Santis, Matteo Foschi, Pooja Khatri, Ahmed Nasreldein, Else Charlotte Sandset, Georgios Tsivgoulis, Lucio D’Anna,Shelagh Coutts, Urs Fischer, Octávio Pontes-Neto, Thanh Nguyen, Guillaume Turc, Simona Sacco

Matteo Foschi Presents The New Expert Guidance on Minor Ischemic Stroke

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AHA Ahmed Nasreldein American Heart Association Else Charlotte Sandset Federico De Santis Georgios Tsivgoulis Guillaume Turc Health Hematology Hemostasis Hemostasis Today Lucio D’Anna Matteo Foschi Medicine Octávio Pontes-Neto Pooja Khatri Shelagh Coutts Simona Sacco stroke Thanh Nguyen thrombosis Urs Fischer
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