Intra-Arterial Tenecteplase After Thrombectomy: Promising but Inconclusive
Ashutosh Jadhav recently shared a post on further management of stroke after successful thrombectomy on X:
”Intra-arterial Tenecteplase for Acute Stroke After Successful Endovascular Therapy.”
Read the full JAMA article here.
A recent study evaluating intra-arterial tenecteplase administered after successful thrombectomy in patients with acute large vessel occlusion (LVO) presenting between 4.5 and 24 hours of symptom onset has shown encouraging yet inconclusive results.
Patients receiving intra-arterial tenecteplase demonstrated a greater likelihood of excellent neurological outcomes at 90 days, without an associated increase in symptomatic intracranial hemorrhage (sICH) or mortality.
However, the optimism was tempered by the fact that none of the secondary efficacy endpoints reinforced the primary findings.
The authors emphasized that further trials are necessary to validate these results and better define the role of intra-arterial tenecteplase in extended-window stroke management.
More on advancements in stroke management featured in Hemostasis Today.
-
Jul 3, 2026, 09:33Abdul Mannan: Not All Type 1 VWD Starts in the VWF Gene
-
Jul 3, 2026, 09:18Aryabhatta Sadhu: Sickle Cell Crisis – When Diagnostics Should Change Therapy
-
Jul 3, 2026, 05:55New Evidence Supports Chromogenic Assays After Hemophilia A Gene Therapy – JTH
-
Jul 3, 2026, 05:50Jacopo Parizzi: Roche’s Non-Malignant Hematology Team Is Looking Ahead to 2027
-
Jul 3, 2026, 05:25Brian A Beh: A New Approach from The George Institute for Global Health Could Transform Stroke Care Before Hospital Arrival
-
Jul 3, 2026, 05:22Deirdre Finnigan: New Insights into Red Blood Cell Biomechanics in Cancer-Associated Anemia
-
Jul 3, 2026, 05:15Danielle Boyle: Collaboration Across Borders Is Helping Shape the Future of ITP Care
-
Jul 3, 2026, 05:05Claire McIvor: One Year at the Stroke Association and Grateful for a Workplace That Made It Possible
-
Jul 2, 2026, 23:11Michael Makris: Join The Cancer Associated Thrombosis Workshop at ISTH 2026