Shaymaa Alhabib on Piezo1 Mutation and Platelet Preactivation State
Shaymaa Alhabib, Student at Bicêtre Hospital, shared on LinkedIn:
”I’m happy to share a study I participated in, now published in the Journal of Thrombosis and Haemostasis
This study shows that Piezo1 gain-of-function mutations prolong channel opening, leading to sustained calcium entry into platelets.
This primes platelets into a preactivated state, helping explain the thrombotic risk in hereditary xerocytosis patients.
A huge thanks to my supervisor Régis Bobe, for the opportunity to be part of this work, and of course to the group headed by Dr. Chrislla Bachelot-Loza for their excellent work!”
Read the full article here.
Article: Piezo1 gain of function induces a platelet preactivation state
Authors: Christilla Bachelot-Loza, Aurore Marchelli, Laurie Ruch, Divina El Hamaoui, Julien Demagny, Bruna Salau Grau, Clarisse Mouriaux, Wafa Amara, Anaïs Mehl, Emma Ziessel, Shaymaa Alhabib, My Ngoc Ha, Fatima Zemali, Sophie Gandrille, Véronique Picard, Pierre Mangin, Régis Bobe, Loïc Garçon, Catherine Léon, Pascale Gaussem
Stay updated on all scientific advances with Hemostasis Today.
-
May 30, 2026, 10:27Sartaj Alam: CBC Analyzer – The Backbone of Modern Hematology Diagnostics
-
May 30, 2026, 10:17Factor X Deficiency – From Mild Bruising to Life Threatening Hemorrhage – ICHCC
-
May 30, 2026, 10:06Johann Morelle: Complement Inhibitors Are Reshaping Modern Nephrology
-
May 30, 2026, 09:49Flora Peyvandi: Exploring a Multidisciplinary Care Model for Hemophilia and Rare Diseases
-
May 30, 2026, 08:59Li-Chia Chen: Advancing Patient Care Through Pharmacist Innovation at KUTRRH
-
May 30, 2026, 08:58Ben Creagh-Brown: How Should HI-PEITHO Influence the Management of Intermediate-Risk Pulmonary Embolism?
-
May 30, 2026, 08:56Reidiel Suárez Borges: Understanding the INR in Anticoagulation Management
-
May 29, 2026, 17:23Rita Schwab: Current Clinical Management of Trauma without the Use of Allogenic Blood Products
-
May 29, 2026, 17:22Brian Schiro: Excited to Provide Guideline Based Care at the Aortic Center