Jim Hoffman։ Targeting NETosis to Improve Perfusion and Reduce Thrombosis in AMI
Jim Hoffman, Former Technical Advisor at Cygnus Technologies, LLC, posted on LinkedIn about a recent article by Robert Chilton et al, published in National Library of Medicine:
”’Overall, understanding the role of NETosis in AMI provides valuable insights into the disease’s pathophysiology and highlights potential therapeutic targets to mitigate the inflammatory and thrombotic components of heart attacks’ Chilton et al 2024
How about helping patients clear NETs/extracellular chromatin from their blood so they can potentially phagocytically remove and catabolize this unwanted chromatin better from their tissues?
This could greatly improve circulatory perfusion, reduce unwanted thrombi formation, and reduce the chances of exacerbated cell death leading to organ dysfunction(s) and failure(s). Poor dietary-related gut dysbiosis, poor insulin and glucose homeostasis are likely directly related and worsened by NETosis dysregulation.”
Title: The web of intrigue: unraveling the role of NETosis within the gut-microbiome-immune-heart axis in acute myocardial infarction and heart failure
Authors: Tai Yasuda, Kate Deans, Aditi Shankar, Robert Chilton
Read the Full Article on National Library of Medicine.
Stay updated on all scientific advances with Hemostasis Today.
-
Apr 14, 2026, 17:32Denise M.: Surviving Sepsis 2026 – The Upstream Revolution
-
Apr 14, 2026, 17:23Meghanath Yenni։ What’s New in Acute Ischemic Stroke in 2026
-
Apr 14, 2026, 17:11Phil Spinella: What Dose of TXA for Children With Severe Traumatic Bleeding Should You Use?
-
Apr 14, 2026, 17:08Abdulrahman Katib: How Endovascular Stenting Is Transforming the Treatment of Severe PTS
-
Apr 14, 2026, 17:00Anna A. Avagyan: Glad to Be Part of EHA Pediatric Hematology-Oncology Course
-
Apr 14, 2026, 16:58Ney Carter Borges: NLRP3 Inhibition in Atherosclerosis – Early Clinical Signal Beyond Lipids
-
Apr 14, 2026, 16:56Saskia Middeldorp: Key Takeaways from the 2026 ACC/AHA Guideline on Acute PE
-
Apr 14, 2026, 16:54Chokri Ben Lamine: Extracorporeal Photopheresis for aGVHD cGVHD Post-SCT – 50 Pearls
-
Apr 14, 2026, 16:49Ahmed Magdi Omar: Key Takeaways From the Latest 2026 Guidelines on Antiplatelet Therapy in AIS