Journal of Thrombosis and Haemostasis (JTH)/LinkedIn
Mar 3, 2026, 16:58
Non-Carrier Mothers of Inv22 Hemophilia A Patients Frequently Harbor Additional F8 Gene Rearrangements – JTH
Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn about a recent article by Eric Manderstedt et al, adding:
“Non-carrier mothers of hemophilia A patients with Inv22 inversions often have other rearrangements
A study analyzing 350 hemophilia A patients revealed that non-carrier mothers of sons with Inv22 inversions frequently harbor additional F8 gene rearrangements, particularly duplications.”
Title: Noncarrier mothers of hemophilia A patients with Intron 22 inversions often have other rearrangements
Authors: Eric Manderstedt, Christina Lind-Halldén, Christer Halldén, Jan Astermar, Hemophilia Inhibitor Genetics Study Cohort
Read the Full Article on JTH.
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