Heghine Khachatryan: Navigating the New Era of Hemophilia Gene Therapy
Heghine Khachatryan, Editor-in-Chief of Hemostasis Today, Head of Hemophilia and Thrombosis Center at Yeolyan Hematology and Oncology Center, shared a post on LinkedIn about a recent article by Pascal Hoffmann et al, published in Journal of Thrombosis and Haemostasis.
“A timely and highly relevant overview on gene therapy in hemophilia.
As we move from substitution therapy toward potential functional cure, the key challenge is no longer innovation itself—but how we implement it safely, equitably, and sustainably in real-world practice.
Important questions remain:
patient selection, long-term safety, durability of expression, and global accessibility.
This article is a valuable step toward structured, evidence-based navigation of this new era.”
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn:
“Overview of gene therapy for hemophilia: questions and answers to navigate the innovation
Gene therapy transforms hemophilia treatment through potentially one-time interventions targeting genetic deficiencies, achieving sustained factor expression and reduced bleeding with AAV-based approaches, though immunosuppressive management remains necessary for post-infusion complications.”
Title: Overview of gene therapy for hemophilia: questions and answers to navigate the innovation
Authors: Pascal Hoffmann, Niccolò Bitto, Vincenzo La Mura, Wolfgang Miesbach
Read the Full Article on Journal of Thrombosis and Haemostasis
Other posts featuring Heghine Khachatryan on Hemostasis Today.
-
Aug 11, 2026, 04:10Haroun Gajraj: CLaCS vs Sclerotherapy – What Does the Evidence Show
-
Aug 11, 2026, 02:54Tareq Abadl: The Ultimate Guide to Clinically Significant Antibodies
-
Aug 10, 2026, 17:35Chokri Ben Lamine: Balancing Holistic Care and Precision in Hematology
-
Aug 10, 2026, 17:14Anna Stanizzi: Patient Blood Management as a New Model of Personalized Care
-
Aug 10, 2026, 17:12Odong Christopher: New Research on Ischemic Stroke Prediction in Uganda
-
Aug 10, 2026, 16:58Jeff Szer AM: Advancing the Management of Paroxysmal Nocturnal Hemoglobinuria
-
Aug 10, 2026, 16:51Suebsarn Ruksakulpiwat։ A New Milestone in the Development of the Stroke Risk Screening Scales
-
Aug 10, 2026, 16:09Preetie Shetty Akkunje: Making Stroke Rehabilitation Accessible in Low-Resource Settings
-
Aug 10, 2026, 15:50The Next Antithrombotic Frontier: GPVI Inhibitors Beyond Aspirin