Anand Padmanabhan: A New Concise Nutshell Review of MGTS as an Emerging Thrombophilia
Anand Padmanabhan, Professor and Clinician-Investigator at Mayo Clinic, shared a post on LinkedIn about a recent article he and his colleagues co-authored, adding:
“We are excited to share our new ‘nutshell’ review on a new thrombotic condition Monoclonal Gammopathy of Thrombotic Significance (MGTS)—a concise (~1000 words) and accessible overview of this emerging thrombophilia.
Congratulations to the authors Adam Kanack, Emily Armstrong, and David Murray on this excellent work!
MGTS is a rapidly evolving entity that we first described a few years ago, and our understanding continues to grow. This review highlights three key subtypes:
- HIT-like
- VITT-like
- Non-HIT/VITT-like
Recognizing these distinct phenotypes is critical—accurate diagnosis is the first step toward appropriate, targeted treatment.
We hope this review helps clinicians and researchers better identify and manage this often debilitating disorder.
As the field evolves, we anticipate refinements in classification and management.
Feel free to reach out with questions or to discuss further.”
Title: Monoclonal gammopathy of thrombotic significance in a nutshell
Authors: Adam J. Kanack, Emily E. Mauch, David L. Murray, Anand Padmanabhan
Read the Full Article on British Journal of Haematology

Stay updated with Hemostasis Today.
-
Apr 6, 2026, 16:20Satyam Arora: Why Are We Transfusing Kids in India?
-
Apr 6, 2026, 16:17Jim Hoffman: Extracorporeal Blood Purification as an Alternative to IVIG and Transfusion in Autoimmune Disease
-
Apr 6, 2026, 16:16Ala Eddin Sagar: What Changed in the New Sepsis Guidelines 2026
-
Apr 6, 2026, 16:13Simon Senanu: Hypersegmented Neutrophils – A Classic Sign of Megaloblastic Anemia
-
Apr 6, 2026, 16:05Peter Bou Dib: Understanding von Willebrand Factor in Bleeding and Thrombotic Disorders
-
Apr 6, 2026, 15:30Rare Diseases, Plasma-Derived Medicines and the Elephant in the Room – Part 3
-
Apr 6, 2026, 15:19Ifeanyichukwu Ifechidere: When PT and APTT Are Normal but Bleeding Persists
-
Apr 6, 2026, 14:59Michal Farkowski: Cardiooncology Also Deals with Arrhythmia
-
Apr 6, 2026, 14:08David McIntosh: What Truly Determines the Safety of Plasma Donation