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Aurore Ughetto: The Hemocompatibility Burden of Micro-Axial Flow Pump Support
Aurore Ughetto/Loop Frontiers
Apr 16, 2026, 09:21

Aurore Ughetto: The Hemocompatibility Burden of Micro-Axial Flow Pump Support

Aurore Ughetto, Cardiac Intensivist and Anesthesiologist at Montpellier University Hospital, shared on LinkedIn:

”One week after our first publication, I’m pleased to share our new publication from the IMPACT project in Critical Care:
‘Bleeding and thrombotic events during micro-axial flow pump support: a European multicenter cohort study’.

We now turn to a critical aspect of micro-axial flow pump support: hemocompatibility.

In a large European multicenter cohort (11 high-volume centers, >1000 patients), nearly 1 in 2 patients experienced a complication during support.

Key findings:

  • Bleeding (34%) and thrombosis (24%) remain frequent
  • Both are independently associated with worse 180-day outcomes
  • They follow distinct clinical profiles, supporting more individualized management strategies

These results highlight how challenging it remains to strike the right balance between preventing thrombosis and avoiding bleeding in cardiogenic shock supported with mAFP.

Above all, this work reflects a collective European effort.

Combining experience across centers, aligning data, and sharing practices is essential to better capture real-world complexity.

Grateful to all teams involved for their trust, commitment, and collaboration.”

Title: Bleeding and thrombotic events during micro-axial flow pump support: A European multicentercohort study

Authors: Aurore Ughetto, Benedikt Schrage, Christophe Vandenbriele, Miloud Cherbi, Antoine Beurton, Monika Fürholz, Wiktor Kuliczkowski, Laurent Bonello, Guillaume Leurent, Ana Hurtado, Philippe Gaudard, Jonas Sundermeyer, Lukas Hunziker, Alexandre Ouattara, Agnieszka Tycinska, Marta Zaleska Kociecka, Hadrien Pichené, Leo Lemarchand, Matias Jacomet, Mikolaj Blaziak, Aneta Klotzka, Alexandre Mansour, Clément Delmas, Emma Chelvi Sendin, Arthur Chouaiki-Perrois, Frederic Bouisset, Chloe Tassain, Fanny Vardon, Julien Imbault, Marie Cuniac, François-Xavier Herion, Erwan Flecher, Nicolas Nesseler, Macarena Otero Escudero, Sara Gonzalez Lastra, Vasileios Panoulas, Benedikt Beer, Angela Dettling, Anna Konopka

Read the Full Article on Critical Care

Aurore Ughetto: The Hemocompatibility Burden of Micro-Axial Flow Pump Support

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Agnieszka Tycińska Alexandre Mansour Alexandre Ouattara Ana Hurtado Aneta Klotzka Angela Dettling Anna Konopka Antoine Beurton Arthur Chouaiki-Perrois Aurore Ughetto Benedikt Beer Benedikt Schrage bleeding Chloe Tassain Christophe Vandenbriele Clément Delmas Critical Care Emma Chelvi Sendin Erwan Flecher Fanny Vardon François-Xavier Herion Frederic Bouisset Guillaume Leurent Hadrien Pichené Health Hematology Hemocompatibility Hemostasis Hemostasis News Hemostasis Today IMPACT Jonas Sundermeyer Julien Imbault Laurent Bonello Leo Lemarchand Lukas Hunziker Macarena Otero Escudero Marie Cuniac Marta Zaleska Kociecka Matias Jacomet Medicine micro-axial flow pump Mikolaj Blaziak Miloud Cherbi Monika Fürholz Nicolas Nesseler Philippe Gaudard Sara Gonzalez Lastra thrombosis Vasileios Panoulas Wiktor Kuliczkowski
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