William Nikolic: How Homocysteine is Associated with Dementia
William Nikolic, Associate Director, MSL at Alfasigma USA, shared a post on LinkedIn about a recent article by A. David Smith et al., published in Journal of Alzheimer’s Disease, adding:
“An international consensus statement and several meta-analyses link hyperhomocysteinemia and age-related cognitive decline.
Based on the evidence, several researchers published an international consensus statement concluding:
‘There was consistent evidence that elevated homocysteine was one of the causes of age-related cognitive decline and dementia.’
Homocysteine sits at the intersection of methylation, vascular health, and neuronal function—making it a biomarker that deserves more attention in conversations about cognitive aging.”
Title: Homocysteine and Dementia: An International Consensus Statement
Authors: A. David Smith, Helga Refsum, Teodoro Bottiglieri, Michael Fenech, Babak Hooshmand, Andrew McCaddon, Joshua W. Miller, Irwin H. Rosenberg, Rima Obeid
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