JAMA/X
Aug 8, 2025, 13:05
HOPE Trial: Alteplase 4.5–24 Hours After Acute Ischemic Stroke
JAMA shared an insightful post on X:
“In patients with salvageable brain tissue identified by perfusion imaging who did not initially receive thrombectomy, alteplase given 4.5 to 24 hours after acute ischemic stroke onset may improve functional outcomes.”
Read the full article here.
Title: Alteplase for Acute Ischemic Stroke at 4.5 to 24 Hours
The HOPE Randomized Clinical Trial
Authors: Ying Zhou, Yaode He, Bruce C. V. Campbell, David S. Liebeskind, Changzheng Yuan, Hui Chen, Yanxing Zhang, Tingyu Yi, Zhongyu Luo, Zuowen Zhang, Changcai Meng, Jianhua Cheng, Hezhong Ouyang, Jin Hu, Fei Wang, Sheng Zhang, Qi Fang, Haitao Hu, Xuting Zhang, Yi Chen, Wansi Zhong, Maarten G. Lansberg, Shenqiang Yan, Min Lou
Stay informed with Hemostasis Today.
acute ischemic stroke
Alteplase
Bruce C. V. Campbell
Changcai Meng
Changzheng Yuan
David S. Liebeskind
Fei Wang
Haitao Hu
Health
Hematology
Hemostasis
Hemostasis Today
Hezhong Ouyang
Hui Chen
JAMA
Jianhua Cheng
Jin Hu
Maarten G Lansberg
Medicine
Min Lou
Qi Fang
Sheng Zhang
Shenqiang Yan
stroke
Thrombectomy
Tingyu Yi
Wansi Zhong
Xuting Zhang
Yanxing Zhang
Yaode He
Yi Chen
Ying Zhou
Zhongyu Luo
Zuowen Zhang
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