Hemostasis Today
NewsFeed
Headlines Hematology Health Medicine VTE ASH Plasma Donation
July, 2026
July 2026
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
2728293031  
Kalyan Roy: Thalassaemia and the Importance of Early Screening
Kalyan Roy/ LinkedIn
May 20, 2026, 15:27

Kalyan Roy: Thalassaemia and the Importance of Early Screening

Kalyan Roy, Transfusion Medicine Specialist at Square Hospitals LTD, shared a post on LinkedIn:

”Thalassaemia

A Lifelong Hematologic Challenge and a Global Public Health Concern

Thalassaemia is one of the most common inherited blood disorders worldwide.

It occurs due to defective production of hemoglobin chains, leading to:

  • Chronic anemia
  • Premature destruction of red cells
  • Reduced oxygen delivery
  • Lifelong medical complications

Major Types

Alpha-thalassaemia

  • Silent carrier
  • Trait
  • HbH disease
  • Hydrops fetalis

Beta-thalassaemia

  • Minor or trait
  • Intermedia
  • Major or transfusion-dependent

Clinical Impact

Severe thalassaemia may cause:

  • Fatigue and pallor
  • Bone deformities
  • Growth retardation
  • Cardiac complications
  • Endocrine dysfunction

Without proper treatment, survival becomes difficult.

Diagnosis

Key investigations include:

  • Complete blood count and peripheral blood film
  • Hemoglobin electrophoresis or HPLC
  • Iron studies
  • Genetic testing

Typical findings:

  • Low MCV and MCH
  • Target cells
  • Elevated HbF or HbA₂

Transfusion and Iron Overload

Regular transfusion remains lifesaving for many patients.

However, repeated transfusions may lead to iron overload affecting:

  • Heart
  • Liver
  • Endocrine glands

Iron chelation therapy is therefore essential.

Prevention Is the Key

Effective prevention strategies include:

  • Carrier screening
  • Premarital counseling
  • Antenatal screening
  • Prenatal diagnosis
  • Public awareness

Early screening can prevent severe thalassaemia in future generations.

Final Thought

Thalassaemia is not merely a laboratory diagnosis —it is a lifelong journey affecting patients, families, and healthcare systems.

Every safe transfusion, every voluntary donor, and every screening initiative contributes to saving lives.”

Kalyan Roy: Thalassaemia and the Importance of Early Screening

Other posts featuring Kalyan Roy on Hemostasis Today.

Health Hematology Hemostasis Hemostasis News Hemostasis Today Kalyan Roy Thalassaemia
NewsFeed