Ifeanyichukwu Ifechidere/LinkedIn
May 27, 2026, 15:25
Ifeanyichukwu Ifechidere: Coagulation Detective Case – The Prolonged APTT Mystery
Ifeanyichukwu Ifechidere, Specialist Biomedical Scientist at Sheffield Teaching Hospitals NHS Foundation Trust, shared a post on LinkedIn:
“Case study: The APTT was 96 seconds.
The patient had no history of bleeding.
So what would You do next?
A 72-year-old patient arrives with:
Extensive spontaneous bruising, with painful muscle haematomas.
There is no previous bleeding disorder and not on anticoagulant.
The coagulation screen shows:
- PT: Normal
- APTT: 96 sec (significantly prolonged)
Now here’s the question for you
- What’s your First thought?
- Heparin contamination?
- Lupus anticoagulant?
- Factor deficiency?
- Acquired inhibitor?
This is where coagulation becomes detective work.
Drop your answer in the comment section below and also check for the full interpretation.”
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