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Muhammad Hamza: Why is Sodium Citrate the Anticoagulant of Choice for Coagulation Tests?
Muhammad Hamza/LinkedIn
Jul 5, 2026, 11:05

Muhammad Hamza: Why is Sodium Citrate the Anticoagulant of Choice for Coagulation Tests?

Muhammad Hamza, Medical Laboratory Technologist, shared a post on LinkedIn:

“Why is Sodium Citrate the Anticoagulant of Choice for Coagulation Tests?

Not all anticoagulants work the same way.

Unlike EDTA, sodium citrate binds calcium reversibly, allowing calcium to be added back during laboratory testing.

This makes it the ideal anticoagulant for evaluating the body’s clotting mechanism.

Common Tests Performed Using the Light Blue Tube:

  1. PT (Prothrombin Time)
  2. APTT
  3. Fibrinogen
  4. Coagulation Factor Assays

Laboratory Tip:

Always ensure the tube is filled to the correct level. An incorrect 9:1 blood-to-anticoagulant ratio can significantly affect coagulation test results.

Remember:

Light Blue Tube: Coagulation Testing.”

Muhammad Hamza: Why is Sodium Citrate the Anticoagulant of Choice for Coagulation Tests?

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